Jorsal, A., Wiggers, H. & McMurray, J. (2018). Heart failure. Epidemiology, pathophysiology, and management of heart failure in diabetes mellitus. Endocrinology and Metabolism Clinics of North America,47(1), A. G. Loachimescu. 117-135. United States of America: Elsevier - WB Saunders. Retrieved from https://doi.org/10.1016/j.ecl.2017.10.007
- Heart failure is a common comorbidity in diabetes and patients with both conditions have a particularly poor prognosis.
- Most clinical outcome trials investigating the effects of glucose-lowering agents have excluded patients with heart failure.
- Glitazones and, possibly, some dipeptidyl peptidase-4 inhibitors, cause an increased risk of developing heart failure and deterioration in existing heart failure.
- One class of drugs, the sodium glucose cotransporter 2 inhibitors, reduce the risk of developing heart failure.
Mary MacKillop Institute for Health Research
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