Tachtsis, B., Smiles, W., Lane, S. C, Hawley, J. A & Camera, DM. (2016). Acute endurance exercise induces nuclear p53 abundance in human skeletal muscle. Frontiers in Physiology,7(144), 1-10. Switzerland: Frontiers Research Foundation. Retrieved from https://doi.org/10.3389/fphys.2016.00144
The tumor suppressor protein p53 may have regulatory roles in exercise response-adaptation processes such as mitochondrial biogenesis and autophagy, although its cellular location largely governs its biological role. We investigated the subcellular localization of p53 and selected signaling targets in human skeletal muscle following a single bout of endurance exercise.
Mary MacKillop Institute for Health Research
Open Access Journal Article
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