Burnett, H., Earley, A., Voors, A. A, Senni, M., McMurray, J., Deschaseaux, C. & Cope, S. (2017). Thirty years of evidence on the efficacy of drug treatments for chronic heart failure with reduced ejection fraction: A network meta-analysis. Circulation: Heart Failure,10(1), 1-13. United States: Lippincott Williams and Wilkins. Retrieved from https://doi.org/10.1161/CIRCHEARTFAILURE.116.003529
Treatments that reduce mortality and morbidity in patients with heart failure with reduced ejection fraction, including angiotensin-converting enzyme inhibitors (ACEI), angiotensin receptor blockers (ARB), β-blockers (BB), mineralocorticoid receptor antagonists (MRA), and angiotensin receptor–neprilysin inhibitors (ARNI), have not been studied in a head-to-head fashion. This network meta-analysis aimed to compare the efficacy of these drugs and their combinations regarding all-cause mortality in patients with heart failure with reduced ejection fraction.
Mary MacKillop Institute for Health Research
Open Access Journal Article