Dalzell, J. R, Seed, A., Berry, C., Whelan, C. J, Petrie, M. C, Padmanabhan, N., Clarke, A., Biggerstaff, F., Hillier, C. & McMurray, JJ. (2014). Effects of neutral endopeptidase (Neprilysin) inhibition on the response to other vasoactive peptides in small human resistance arteries: Studies with thiorphan and omapatrilat. Cardiovascular Therapeutics,32(1), 13-18. United Kingdom: Wiley-Blackwell Publishing Ltd.. Retrieved from https://doi.org/10.1111/1755-5922.12053
New compounds with neprilysin or neutral endopeptidase (NEP) inhibiting activity are under clinical investigation in heart failure and hypertension. We investigated the effect of NEP inhibition on the functional vasomotor responses to a range of vasoactive peptides in human blood vessels.
Mary MacKillop Institute for Health Research