Authors
Eileen Moore
Alastair Mander
David Ames
Mark A. Kotowicz
Ross Carne
Henry Brodaty
Michael Clifford Woodward
Karen Boundy
Kathryn A. Ellis
Ashley I. Bush
Noel G. Faux
Ralph N. Martins
Cassandra Szoeke, Australian Catholic UniversityFollow
Christopher C. Rowe
David Watters
Publication Date
2013
Publication Details
Moore, E., Mander, A., Ames, D., Kotowicz, M. A, Carne, R., Brodaty, H., Woodward, M. C, Boundy, K., Ellis, K. A, Bush, A. I, Faux, N. G, Martins, R. N, Szoeke, C., Rowe, C. C & Watters, D. (2013). Increased risk of cognitive impairment in patients with diabetes is associated with metformin. Diabetes Care, Retrieved from https://doi.org/10.2337/dc13-0229
Abstract
OBJECTIVE To investigate the associations of metformin, serum vitamin B12, calcium supplements, and cognitive impairment in patients with diabetes. RESEARCH DESIGN AND METHODS Participants were recruited from the Primary Research in Memory (PRIME) clinics study, the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging, and the Barwon region of southeastern Australia. Patients with Alzheimer disease (AD) (n = 480) or mild cognitive impairment (n = 187) and those who were cognitively intact (n = 687) were included; patients with stroke or with neurodegenerative diseases other than AD were excluded. Subgroup analyses were performed for participants who had either type 2 diabetes (n = 104) or impaired glucose tolerance (n = 22).
School/Institute
Institute for Health and Ageing
Document Type
Journal Article
Access Rights
ERA Access