Kanis, J., McCloskey, E., Harvey, N. C & Leslie, WD. (2019). FRAX: Assessment of Fracture Risk. J. P. Bilezikian. Primer on the metabolic bone diseases and disorders of mineral metabolism 331-339. United States of America: Wiley-Blackwell. Retrieved from https://doi.org/10.1002/9781119266594.ch41
A major objective of fracture risk assessment is to enable the targeting of interventions to those at need and avoid unnecessary treatment in those at low risk of fracture. Several risk prediction models have been developed, but the most widely used is the Fracture Risk Assessment Tool (FRAX). FRAX is a computer‐based algorithm that is intended for primary care, calculates fracture probability from easily obtained clinical risk factors in men aged 40 years or more and postmenopausal women. Fracture probability is computed taking into account both the risk of fracture and the risk of death. The use of clinical risk factors alone provides a gradient of risk that lies between 1.4 and 2.1, depending upon age and the type of fracture predicted. FRAX should not be considered as a gold standard in patient assessment, but rather as a reference platform. FRAX has been recommended as a screening tool to detect osteoporosis.
Mary MacKillop Institute for Health Research
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