The Mary MacKillop Institute for Health Research aims to identify critical gaps within community and healthcare services, with an explicit goal to improve health outcomes (and a focus on vulnerable groups) via innovative individual, community and health service-focused programs.

Collaborating on projects nationally and internationally, The MacKillop invests in people and communities across Australia and beyond its borders.

Through research that responds to real needs, researchers are working to improve the well-being of people locally and globally so that they can lead full, healthy lives.

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Submissions from 2014

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Comorbidities and differential diagnosis in heart failure with preserved ejection fraction, Ross T. Campbell and John J. V. McMurray

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Risk factors for heart failure in patients with type 2 diabetes mellitus and stage 4 chronic kidney disease treated with bardoxolone methyl, Melanie P. Chin, Danielle Wrolstad, George L. Bakris, Glenn M. Chertow, Dick de Zeeuw, Angie Goldsberry, Peter G. Linde, Peter A. McCullough, John J. V. McMurray, Janet T. Wittes, and Colin J. Meyer

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Access to cardiac rehabilitation does not equate to attendance, Robyn A. Clark, Neil Coffee, Dorothy Turner, Kerena Eckert, Deborah Van Gaans, David Wilkinson, Simon Stewart, and Andrew Tonkin

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Worsening heart failure, a critical event during hospital admission for acute heart failure: Results from the VERITAS study, Gad Cotter, Marco Metra, Beth A. Davison, Stefanie Senger, Robert C. Bourge, John G. F. Cleland, Guillaume Jondeau, Henry Krum, Christopher M. O'Connor, John D. Parker, Guillermo Torre-Amione, Dirk J. van Veldhuisen, Olga Milo, Isaac Kobrin, Maurizio Rainisio, John J. V. McMurray, and John R. Teerlink

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The effects of progressive resistance training combined with a whey-protein drink and vitamin D supplementation on glycaemic control, body composition and cardiometabolic risk factors in older adults with type 2 diabetes : Study protocol for a randomized controlled trial, Robin Daly, Eliza Miller, David Dunstan, Deborah Kerr, Vicky Solah, David Menzies, and Caryl Nowson

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Effects of neutral endopeptidase (Neprilysin) inhibition on the response to other vasoactive peptides in small human resistance arteries: Studies with thiorphan and omapatrilat, Jonathan R. Dalzell, Alison Seed, Colin Berry, Carol J. Whelan, Mark C. Petrie, Neal Padmanabhan, Amanda Clarke, Fiona Biggerstaff, Christopher Hillier, and John J.V. McMurray

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Worsening renal function and outcome in heart failure patients with preserved ejection fraction and the impact of angiotensin receptor blocker treatment, Kevin Damman, Ana C. Perez, Inder S. Anand, Michel Komajda, Robert S. McKelvie, Michael R. Zile, Barrie Massie, Peter E. Carson, and John J.V. McMurray

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Current evidence on treatment of patients with chronic systolic heart failure and renal insufficiency: Practical considerations from published data, Kevin Damman, W. H. Wilson Tang, G. Michael Felker, Johan Lassus, Faiez Zannad, Henry Krum, and John J.V. McMurray

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The association between meteorological events and acute heart failure: New insights from ASCEND-HF, Debraj Das, Jeffery A. Bakal, Cynthia M. Westerhout, Adrian F. Hernandez, Christopher M. O'Connor, Dan Atar, John J.V. McMurray, Paul W. Armstrong, and Justin A. Ezekowitz

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Managing sedentary behavior to reduce the risk of diabetes and cardiovascular disease, Paddy C. Dempsey, Neville Owen, Stuart J. H. Biddle, and David Wayne Dunstan

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Associations of television viewing time with adults' well-being and vitality, Paddy Dempsey, Bethany Howard, Brigid Lynch, Neville Owen, and David Dunstan

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Influence of hospitalization for cardiovascular versus noncardiovascular reasons on subsequent mortality in patients with chronic heart failure across the spectrum of ejection fraction, Akshay S. Desai, Brian L. Claggett, Marc A. Pfeffer, Natalie Bello, Peter Finn, Christopher B. Granger, John McMurray, Stuart J. Pocock, Karl Swedberg, Salim Yusuf, and Scott Solomon

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Building skill in heart failure self-care among community dwelling older adults: Results of a pilot study, Victoria Vaughan Dickson, Gail D. Eramo Melkus, Stuart Katz, Alissa Levine-Wong, Judy Dillworth, Charles M. Cleland, and Barbara Riegel

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Skeletal muscle disuse atrophy is not attenuated by dietary protein supplementation in healthy older men, Marlou L. Dirks, Benjamin T. Wall, Rachel Nilwik, Daniëlle H. J. M. Weerts, Lex B. Verdijk, and Luc J. C. van Loon

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Neuromuscular electrical stimulation prevents muscle disuse atrophy during leg immobilization in humans, Marlou L. Dirks, Benjamin T. Wall, Tim Snijders, C. L. P. Ottenbros, Lex B. Verdijk, and Luc J. C. Van Loon

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Daily physical activity in stable heart failure patients, Manon Dontje, Martje van der Wal, Ronald Stolk, Johan Brugemann, Tiny Jaarsma, Petra Wijtvliet, C Van Der Schans, and Mathieu de Greef

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Ethnic difference in the prevalence of angina pectoris in Sami and non-Sami populations: The SAMINOR study, Bent-Martin Eliassen, S Graff-Iversen, Marita Melhus, Maja-Lisa Loechen, and Ann Ragnhild Broderstad

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Subclinical cardiovascular disease is associated with a high glomerular filtration rate in the nondiabetic general population, B. O. Eriksen, Maja-Lisa Løchen, Kjell A. Arntzen, Geir Bertelsen, Britt-Ann W. Eilertsen, Therese von Hanno, Marit Herder, Trond G. Jenssen, Ulla D. Mathisen, Toralf Melsom, Inger Njølstad, Marit D. Solbu, Ingrid Toft, and Ellisiv B. Mathiesen

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Variable effects of 12 weeks of omega-3 supplementation on resting skeletal muscle metabolism, Christopher J. Gerling, Jamie Whitfield, Kazutaka Mukai, and Lawrence L. Spriet

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Sex-specific cardiovascular structure and function in heart failure with preserved ejection fraction, Mauro Gori, Carolyn S. P. Lam, Deepak K. Gupta, Angela B. S. Santos, Susan Cheng, Amil M. Shah, Brian L. Claggett, Michael R. Zile, Elisabeth Kraigher-Krainer, Burkert Pieske, Adriaan A. Voors, Milton Packer, Toni Bransford, Martin P. Lefkowitz, John J. V. McMurray, and Scott D. Solomon

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Association between renal function and cardiovascular structure and function in heart failure with preserved ejection fraction, Mauro Gori, Michele Senni, Deepak K. Gupta, David M. Charytan, Elisabeth Kraigher-Krainer, Burkert Pieske, Brian L. Claggett, Amil M. Shah, Angela B. S. Santos, Michael R. Zile, Adriaan A. Voors, John J. V. McMurray, Milton Packer, Toni Bransford, Martin Lefkowitz, and Scott D. Solomon

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Carbohydrate coingestion delays dietary protein digestion and absorption but does not modulate postprandial muscle protein accretion, Stefan H. M. Gorissen, Nicholas A. Burd, Henrike M. Hamer, Annemie P. Gijsen, Bart B. L. Groen, and Luc J. C. van Loon

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Long-term cardiovascular consequences of Rose angina at age 20-54 years: 29-years' follow-up of the Tromso Study, Sidsel Graff-Iversen, Tom Wilsgaard, Ellisiv B. Mathiesen, Inger Njølstad, and Maja-Lisa Løchen

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Prognostic effect of high-sensitive troponin t assessment in elderly patients with chronic heart failure : results from the CORONA Trial, Jørgen Gravning, Erik Tandberg Askevold, Ståle Nymo, Thor Ueland, John Wikstrand, John McMurray, Pål Aukrust, Lars Gullestad, and John Kjekshus

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Skeletal muscle capillary density and microvascular function are compromised with aging and type 2 diabetes, Bart B. L. Groen, Henrike M. Hamer, Tim Snijders, Janneau Van Kranenburg, Dionne Frijns, Hans Vink, and Luc J.C. van Loon

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Venous thromboembolism increases the risk of atrial fibrillation: The Tromsø Study, Erin M. Hald, Kristin F. Enga, Maja-Lisa Løchen, Ellisiv B. Mathiesen, Inger Njølstad, Tom Wilsgaard, Sigrid K. Braekkan, and John-Bjarne Hansen

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Establishing reference values for central blood pressure and its amplification in a general healthy population and according to cardiovascular risk factors, Annie Herbert, John Cruickshank, Stephane Laurent, and Pierre Boutouyrie

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Omega-3 supplementation alters mitochondrial membrane composition and respiration kinetics in human skeletal muscle, E. A. F. Herbst, S. Paglialunga, C. Gerling, Jamie Whitfield, K. Mukai, Adrian Chabowski, G. J. F. Heigenhauser, L. L. Spriet, and Graham P. Holloway

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High-sensitivity troponin I for risk assessment in patients with atrial fibrillation: Insights from the apixaban for reduction in stroke and other thromboembolic events in atrial fibrillation (ARISTOTLE) trial, Ziad M. Hijazi, Agneta Siegbahn, Ulrika Andersson, Christopher B. Granger, John H. Alexander, Dan Atar, Bernard J. Gersh, Puneet Mohan, Veli-Pekka Harjola, John Horowitz, Steen Husted, Elaine Hylek, Renato D. Lopes, John McMurray, and Lars Wallentin

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High-sensitivity troponin T and risk stratification in patients with atrial fibrillation during treatment with apixaban or warfarin, Ziyad Hijazi, Lars Wallentin, Agneta Siegbahn, Ulrika Andersson, John H. Alexander, Dan Atar, Bernard J. Gersh, Michael Hanna, Veli-Pekka Harjola, John D. Horowitz, Steen Husted, Elaine M. Hylek, Renato D. Lopes, John J.V. McMurray, and Christopher B. Granger

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Communicating prognosis and end-of-life care to heart failure patients : A survey of heart failure nurses' perspectives, Lisa Hjelmfors, Anna Stromberg, Maria Friedrichsen, Jan Martensson, and Tiny Jaarsma

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Chromium enhances insulin responsiveness via AMPK, Nolan John Hoffman, Brent A. Penque, Kirk M. Habegger, Whitney Sealls, Lixuan Tackett, and Jeffrey S. Elmendorf

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Rationale for and design of the Acarbose Cardiovascular Evaluation (ACE) trial, Rury R. Holman, Mary A. Bethel, Juliana C. N. Chan, Jean Louis Chiasson, Zoë Doran, Junbo Ge, Hertzel C. Gerstein, Yong Huo, John J. McMurray, Lars Ryden, Winitha Liyanage, Stefan Schröder, Michal Tendera, Michael J. Theodorakis, Jaakko Tuomilehto, Wenying Yang, Dayi Hu, and Changyu Pan

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Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk, Oddgeir L. Holmen, He Zhang, Yanbo Fan, Daniel H. Hovelson, Ellen Schmidt, Wei Zhou, Yanhong Guo, Ji Zhang, Arnulf Langhammer, Maja-Lisa Løchen, Santhi K. Ganesh, Lars Vatten, Frank Skorpen, Havard Dalen, Jifeng Zhang, Subramaniam Pennathur, Jin Chen, Carl Platou, Ellisiv B. Mathiesen, Tom Wilsgaard, Inger Njølstad, Michael Boehnke, Y. Eugene Chen, Goncalo R. Abecasis, Kristian Hveem, and Cristen J. Willer

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No large-effect low-frequency coding variation found for myocardial infarction, Oddger L. Holmen, He Zhang, Wei Zhou, Ellen Schmidt, Daniel H. Hovelson, Arnulf Langhammer, Maja-Lisa Loechen, Santhi K. Ganesh, E. B. Mathiesen, L. Vatten, Carl Platou, Tom Wilsgaard, Jin Chen, Frank Skorpen, Havard Dalen, Michael Boehnke, Goncalo R. Abecasis, I. Njolstad, Kristian Hveem, and Cristen J. Willer

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Digitalis for treatment of heart failure in patients in sinus rhythm, William B. Hood, Antonio L. Dans, Gordon H. Guyatt, Roman Jaeschke, and John J. V. McMurray

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Impact of baseline physical activity and diet behavior on metabolic syndrome in a pharmaceutical trial: Results from NAVIGATOR, Kim M. Huffman, Jie-Lena Sun, Laine Thomas, Connie W. Bales, Robert M. Califf, Thomas Yates, Melanie J. Davies, Rury R. Holman, John J. V. McMurray, M. Angelyn Bethel, Jaakko Tuomilehto, Steven M. Haffner, and William E. Kraus

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Implementing guideline based heart failure care in the northern territory: Challenges and solutions, Pupalan Iyngkaran, Melanie Harris, Marcus Ilton, Nadarajan Kangaharan, Malcolm Battersby, Simon Stewart, and Alex Brown

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Sexual dysfunction in heart failure patients, Tiny Jaarsma, Bengt Fridlund, and Jan Martensson

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20 things you didn't know about sex and heart disease, Tiny Jaarsma and Elaine Steinke

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20 things you didn't know about European cardiac nurses, Tiny Jaarsma and Anna Stromberg

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Heart failure clinics are still useful (more than ever?), Tiny Jaarsma and Anna Strömberg

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Microvolt T-wave alternans testing in patients recently hospitalized with decompensated heart failure: Reply, Colette E. Jackson, Rachel C. Myles, and John McMurray

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Up-titration of allopurinol in patients with gout, Claudine G. Jennings, Isla S. Mackenzie, Rob Flynn, Ian Ford, George Nuki, Raffaele De Caterina, Philip L. Riches, Stuart H. Ralston, Thomas M. MacDonald, Stuart Ralston, Evelyn Findlay, Jesper Hallas, Chris J. Hawkey, Matthew Walters, John Webster, John J. V. McMurray, Fernando Perez Ruiz, and John Harvie

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Elevation in high-sensitivity troponin t in heart failure and preserved ejection fraction and influence of treatment with the angiotensin receptor neprilysin inhibitor LCZ696, Pardeep Jhund, Brian L. Claggett, Adriaan A. Voors, Michael R. Zile, Milton Packer, Burkert Pieske, Elisabeth Kraigher-Krainer, Amil Shah, Margaret F. Prescott, Victor C. Shi, Marty P. Lefkowitz, John McMurray, and Scott Solomon

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Independence of the blood pressure lowering effect and efficacy of the angiotensin receptor neprilysin inhibitor, LCZ696, in patients with heart failure with preserved ejection fraction: An analysis of the PARAMOUNT trial, Pardeep S. Jhund, Brian L. Claggett, Milton Packer, Michael R. Zile, Adriaan A. Voors, Burkert Pieske, Martin P. Lefkowitz, Victor C. Shi, Toni Bransford, John J. V. McMurray, and Scott D. Solomon

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Association between prehospital delay and subsequent clinical course in patients with/hospitalized for heart failure, Joanna Johansson, Rhodri Williams, Paul Rainer, Ian McKeown, and Morgan Williams

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Towards tailoring of self-management for patients with chronic heart failure or chronic obstructive pulmonary disease : A protocol for an individual patient data meta-analysis, Nini Jonkman, Heleen Westland, Jaap Trappenburg, Rolf Groenwold, Tanja Effing-Tijdhof, Thierry Troosters, Job van der Palen, Jean Bourbeau, Tiny Jaarsma, Arno Hoes, and Marieke Schuurmans

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High-sensitivity C-reactive protein in acute heart failure: Insights from the ASCEND-HF trial, Andreas P. Kalogeropoulos, W. H. Wilson Tang, Amy Hsu, G. Michael Felker, Adrian F. Hernandez, Richard W. Troughton, Adriaan A. Voors, Stefan D. Anker, Marco Metra, John J. V. McMurray, Barry M. Massie, Justin A. Ezekowitz, Robert M. Califf, Christopher M. O'Connor, Randall C. Starling, and Javed Butler

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Circulating cardiac troponin T exhibits a diurnal rhythm, Lieke J. J. Klinkenberg, Jan-Willem van Dijk, Frans E. S. Tan, Luc J.C. van Loon, Marja P. van Dieijen-Visser, and Steven J. R. Meex

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Exergaming to increase the exercise capacity and daily physical activity in heart failure patients : A pilot study, Leonie Klompstra, Tiny Jaarsma, and Anna Stromberg

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Exergaming in older adults : A scoping review and implementation potential for patients with heart failure, Leonie Verheijden Klompstra, Tiny Jaarsma, and Anna Stromberg

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What puts heart failure patients at risk for poor medication adherence?, George J. Knafl and Barbara Riegel

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Impaired systolic function by strain imaging in heart failure with preserved ejection fraction, Elisabeth Kraigher-Krainer, Amil M. Shah, Deepak K. Gupta, Angela Santos, Brian Claggett, Burkert Pieske, Michael R. Zile, Adriaan A. Voors, Martin P. Lefkowitz, Milton Packer, John J.V. McMurray, and Scott D. Solomon

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Cost-effectiveness of eplerenone in patients with systolic heart failure and mild symptoms, Dawn Lee, Koo Wilson, Ron Akehurst, Martin R. Cowie, Faiez Zannad, Henry Krum, Dirk J. van Veldhuisen, John Vincent, Bertram Pitt, and John J. V. McMurray

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Perceived caring needs in patient-partner dyads affected by heart failure : A qualitative study, Maria Liljeroos, Susanna Agren, Tiny Jaarsma, and Anna Stromberg

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Acute hyperglycemia impairs vascular function in healthy and cardiometabolic diseased subjects: Systematic review and meta-analysis, Jennifer Loader, Raquel Graham, Chris Richardson, Chizimuzo Okoli, Laura Struik, and Joan Bottorff

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Long-term follow-up in optimally treated and stable heart failure patients : Primary care vs. heart failure clinic. Results of the COACH-2 study, Marie-Louise Luttik, Tiny Jaarsma, Peter van Geel, Maaike Brons, Hans Hillege, Arno Hoes, Richard de Jong, Gerard Linssen, Dirk Lok, Marjolein Berge, and Dirk van Veldhuisen

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Protocol of the Febuxostat versus Allopurinol Streamlined Trial (FAST): A large prospective, randomised, open, blinded endpoint study comparing the cardiovascular safety of allopurinol and febuxostat in the management of symptomatic hyperuricaemia, Thomas M. MacDonald, Ian Ford, George Nuki, Isla S. Mackenzie, Raffaele De Caterina, Evelyn Findlay, Jesper Hallas, Christopher J. Hawkey, Stuart Ralston, Matthew Walters, John Webster, John McMurray, Fernando Perez Ruiz, and Claudine G. Jennings

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Effect of spironolactone on 30-day death and heart failure rehospitalization (from the COACH study), Alan Maisel, Yang Xue, Dirk van Veldhuisen, Adriaan Voors, Tiny Jaarsma, Peter Pang, Javed Butler, Bertram Pitt, Paul Clopton, and Rudolf de Boer

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Protein co-ingestion strongly increases postprandial insulin secretion in type 2 diabetes patients, Ralph J. F. Manders, Dominique Hansen, Antoine H. G. Zorenc, Paul Dendale, Joris Kloek, Wim H. M. Saris, and Luc J. C. van Loon

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Heart failure: A cardiovascular outcome in diabetes that can no longer be ignored, John J. V. McMurray, Hertzel C. Gerstein, Rury R. Holman, and Marc A. Pfeffer

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Angiotensin-neprilysin inhibition versus enalapril in heart failure, John J. V. McMurray, Milton Packer, Akshay S. Desai, Jianjian Gong, Martin P. Lefkowitz, Adel R. Rizkala, Jean L. Rouleau, Victor C. Shi, Scott D. Solomon, Karl Swedberg, and Michael R. Zile

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Baseline characteristics and treatment of patients in Prospective Comparison of ARNI with ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure trial (PARADIGM-HF), John J. V. McMurray, Milton Packer, Akshay S. Desai, Jianjian Gong, Martin P. Lefkowitz, Adel R. Rizkala, Jean L. Rouleau, Victor C. Shi, Scott D. Solomon, Karl Swedberg, and Michael R. Zile

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Grb10 deletion enhances muscle cell proliferation, differentiation and GLUT4 plasma membrane translocation, Nancy Mokbel, Nolan John Hoffman, Christian M. Girgis, Lewin Small, Nigel Turner, Roger J. Daly, Gregory J. Cooney, and Lowenna J. Holt

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Identification of symptom clusters among patients with heart failure : An international observational study, Debra Moser, Kyoung Suk Lee, Jia-Rong Wu, Gia Mudd-Martin, Tiny Jaarsma, Tsuey-Yuan Huang, Xui-Zhen Fan, Anna Stromberg, Terry Lennie, and Barbara Riegel

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The impact of kidney function on outcomes following high risk myocardial infarction: Findings from 27 610 patients, George V. Moukarbel, Zi-Fan Yu, Kenneth Dickstein, Yingxin Hou, Janet T. Wittes, John J. V. McMurray, Bertram Pitt, Faiez Zannad, Marc A. Pfeffer, and Scott D. Solomon

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Patient participation in patients with heart failure receiving structured home care - A prospective longitudinal study, Lena Näsström, Tiny Jaarsma, Ewa Idvall, Kristofer Arestedt, and Anna Stromberg

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Workplace sitting and height-adjustable workstations : A randomized controlled trial, Maike Neuhaus, Genevieve Healy, David Dunstan, Neville Owen, and Elizabeth Eakin

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Iterative development of Stand Up Australia: A multi-component intervention to reduce workplace sitting, Maike Neuhaus, Genevieve Healy, Brianna Fjeldsoe, Sheleigh Lawler, Neville Owen, David Dunstan, Anthony LaMontagne, and Elizabeth Eakin

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Inflammatory cytokines in chronic heart failure: Interleukin-8 is associated with adverse outcome. Results from CORONA, Ståle H. Nymo, Johannes Hulthe, Thor Ueland, John J. V. McMurray, John Wikstrand, Erik Tandberg Askevold, Arne Yndestad, Lars Gullestad, and Pål Aukrust

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Uric acid is associated with future atrial fibrillation: an 11-year follow-up of 6308 men and women - The Tromso Study, Audhild Nyrnes, Ingrid Toft, I. Njolstad, E. B. Mathiesen, Tom Wilsgaard, John-Bjarne Hansen, and Maja-Lisa Loechen

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History of atrial fibrillation as a risk factor in patients with heart failure and preserved ejection fraction, Oludamilola W. Oluleye, Thomas S. Rector, Sithu Win, John McMurray, Michael R. Zile, Michel Komajda, Robert McKelvie, Barry Massie, Peter E. Carson, and Inder S. Anand

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The obesity paradox in heart failure patients with preserved versus reduced ejection fraction: A meta-analysis of individual patient data, R. Padwal, Finlay A. McAlister, John J.V. McMurray, M. R. Cowie, Michael W. Rich, Stuart J. Pocock, Karl Swedberg, Aldo Pietro Maggioni, Greg D. Gamble, Cono A. Ariti, Nikki Earle, Gillian A. Whalley, Katrina K. Poppe, Robert N. Doughty, and Antoni Bayes-Genis

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Structural basis for phosphorylation and lysine acetylation crosstalk in a kinase motif associated with myocardial ischemia and cardioprotection, Benjamin L. Parker, Nicholas E. Shepherd, Sophie Trefely, Nolan John Hoffman, Melanie Y. White, Kasper Engholm-Keller, Brett D. Hambly, Martin R. Larsen, David E. James, and Stuart J. Cordwell

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Hypotension during hospitalization for acute heart failure is independently associated with 30-day mortality : Findings from ASCEND-HF, Priyesh A. Patel, Gretchen M. Heizer, Christopher M. O'Connor, Phillip J. Schulte, Kenneth Dickstein, Justin A. Ezekowitz, P W. Armstrong, Vic Hasselblad, Roger M. Mills, John McMurray, Randall C. Starling, W. H. Wilson Tang, Robert M. Califf, and Adrian F. Hernandez

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Workplace Sitting Breaks Questionnaire (SITBRQ) : An assessment of concurrent validity and test-retest reliability, Zeljko Pedisic, Jason Bennie, Anna Timperio, David Crawford, David Dunstan, Adrian Bauman, and Jo Salmon

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Thyroid-stimulating hormone and clinical outcomes: The CORONA trial (controlled rosuvastatin multinational study in heart failure), Ana Cristina Perez, Pardeep S. Jhund, David S. Stott, Lars Gullestad, John G. F. Cleland, Dirk J. van Veldhuisen, John Wikstrand, John Kjekshus, and John McMurray

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Fatigue as a predictor of outcome in patients with heart failure: Analysis of CORONA (Controlled rosuvastatin multinational trial in heart failure), Ana Cristina Perez-Moreno, Pardeep S. Jhund, Michael R. Macdonald, Mark C. Petrie, John G. F. Cleland, Michael Böhm, Dirk J. van Veldhuisen, Lars Gullestad, John Wikstrand, John Kjekshus, James D. Lewsey, and John J.V. McMurray

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Metformin for non-diabetic patients with coronary heart disease (the CAMERA study): A randomised controlled trial, David Preiss, Suzanne M. Lloyd, Ian Ford, John J. V. McMurray, Rury R. Holman, Paul Welsh, Miles Fisher, Chris J. Packard, and Naveed Sattar

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Risk prediction in patients with heart failure: A systematic review and analysis, Kazem Rahimi, Derrick A. Bennett, Nathalie Conrad, Timothy M. Williams, Joyee Basu, Jeremy Dwight, Mark Woodward, Anushka Patel, John McMurray, and Stephen Macmahon

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The role of dietary protein and vitamin D in maintaining musculoskeletal health in postmenopausal women: A consensus statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO), Rene Rizzoli, John C. Stevenson, Jürgen M. Bauer, Lucas J.C. Van Loon, Stéphane Walrand, John A. Kanis, Cyrus Cooper, Maria Luisa Brandi, Adolfo Diez-Perez, and Jean Yves Reginster

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Effect of rosuvastatin on repeat heart failure hospitalizations: The CORONA trial (controlled rosuvastatin multinational trial in heart failure), Jennifer K. Rogers, Pardeep S. Jhund, Ana-Cristina Perez, Michael Böhm, John G. Cleland, Lars Gullestad, John Kjekshus, Dirk J. van Veldhuisen, John Wikstrand, Hans Wedel, John J.V. McMurray, and Stuart J. Pocock

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Analysing recurrent hospitalizations in heart failure: A review of statistical methodology, with application to CHARM-preserved, Jennifer K. Rogers, Stuart J. Pocock, John J. V. McMurray, Christopher B. Granger, Eric L. Michelson, Jan Ostergren, Marc A. Pfeffer, Scott D. Solomon, Karl Swedberg, and Salim Yusuf

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Outcomes trajectories in children with epilepsy : Hypotheses and methodology of a Canadian Longitudinal Observational Study, Gabriel Ronen, David Streiner, Michael Boyle, Charles Cunningham, Lucyna Lach, Leonard Verhey, Nora Fayed, Karen Chen, and Peter Rosenbaum

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Incidence, determinants, and prognostic significance of hyperkalemia and worsening renal function in patients with heart failure receiving the mineralocorticoid receptor antagonist eplerenone or placebo in addition to optimal medical therapy: Results from the eplerenone in mild patients hospitalization and survival study in heart failure (EMPHASIS-HF), Patrick Rossignol, Daniela Dobre, John McMurray, Karl Swedberg, Henry Krum, Dirk J. van Veldhuisen, Harry Shi, Michael Messig, John Vincent, Nicolas Girerd, G. Bakris, Bertram Pitt, and Faiez Zannad

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Multidrug and optimal heart failure therapy prescribing in older general practice populations : A clinical data linkage study, Claire Rushton, Anna Stromberg, Tiny Jaarsma, and Umesh Kadam

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Left ventricular dyssynchrony in patients with heart failure and preserved ejection fraction, Angela B. S. Santos, Elisabeth Kraigher-Krainer, Natalie Bello, Brian L. Claggett, Michael R. Zile, Burkert Pieske, Adriaan A. Voors, John J. V. McMurray, Milton Packer, Toni Bransford, Marty P. Lefkowitz, Amil M. Shah, and Scott D. Solomon

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Impaired left atrial function in heart failure with preserved ejection fraction, Angela B. S. Santos, Elisabeth Kraigher-Krainer, Deepak K. Gupta, Brian L. Claggett, Michael R. Zile, Burkert Pieske, Adriaan A. Voors, Marty P. Lefkowitz, Toni Bransford, Victor C. Shi, Milton Packer, John J. V. McMurray, Amil M. Shah, and Scott D. Solomon

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Factors associated with delay in seeking care for acute decompensated heart failure, Kristen A. Sethares, Mary-Elizabeth Sosa, Paige Fisher, and Barbara Riegel

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Red cell distribution width is associated with incident myocardial infarction in a general population: The Tromsø Study, Tove Skjelbakken, Jostein Lappegard, Trygve S. Ellingsen, Elizabeth Barret-Connor, Jan Brox, Maja-Lisa Løchen, Inger Njølstad, Tom Wilsgaard, Ellisiv B. Mathiesen, Sigrid K. Braekkan, and John-Bjarne Hansen

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Acute dietary protein intake restriction is associated with changes in myostatin expression after a single bout of resistance exercise in healthy young men, Tim Snijders, Lex B. Verdijk, Bryon R. McKay, Joey S. J. Smeets, Janneau van Kranenburg, Bart B. B. Groen, Gianni Parise, Paul L. Greenhaff, and Luc J. C. van Loon

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Muscle disuse atrophy is not accompanied by changes in skeletal muscle satellite cell content, Tim Snijders, Benjamin T. Wall, Marlou L. Dirks, Joan M. G. Senden, Fred Hartgens, John Dolmans, Mario Losen, Lex B. Verdijk, and Luc J. C. van Loon

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Using brief motivational interviewing to address the complex needs of a challenging patient with heart failure, Michael Stawnychy, Ruth Masterson Creber, and Barbara Riegel

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Intervening to reduce workplace sitting time : How and when do changes to sitting time occur?, Samantha Stephens, Elisabeth Winkler, Stewart Trost, David Dunstan, Elizabeth Eakin, Sebastien Chastin, and Genevieve Healy

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Context matters in heart failure self-care: A qualitative systematic review, Patricia H. Strachan, Kay Currie, Karen Harkness, Melisa A. Spaling, and Alexander Michael Clark

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Employers and doctors need to recognise and respond to the health hazards of too much sedentary time, Leon Straker, Genevieve N. Healy, Rohan Atherton, and David Wayne Dunstan

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Influence of age and gender on fat mass, fat-free mass and skeletal muscle mass among Australian adults : The Australian Diabetes, Obesity and Lifestyle Study (AUSDIAB), Claudia Strugnell, David Dunstan, Dianna Magliano, Paul Zimmet, Jonathan Shaw, and Robin Daly

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Single-nucleotide polymorphism, rs1799941 in the Sex Hormone- Binding Globulin (SHBG) gene, related to both serum testosterone and SHBG levels and the risk of myocardial infarction, type 2 diabetes, cancer and mortality in men: The Tromsø Study, Johan Svartberg, Henrik Schirmer, Tom Wilsgaard, E. B. Mathiesen, I. Njolstad, Maja-Lisa Loechen, and Rolf Jorde

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A Pilot Study of Audio-Visual Stimulation as a Self-Care Treatment for Insomnia in Adults with Insomnia and Chronic Pain, Hsin Yi Jean Tang, Michael V. Vitiello, Michael Perlis, Jun James Mao, and Barbara Riegel