Krum, H., Elsik, M., Schneider, H. G, Ptaszynska, A., Black, M., Carson, P. E, Komajda, M., Massie, B., McKelvie, R., McMurray, J., Zile, M. R & Anand, IS. (2011). Relation of peripheral collagen markers to death and hospitalization in patients with heart failure and preserved ejection fraction : results of the I-PRESERVE collagen substudy. Circulation: Heart Failure,4(5), 561-568. United States: Lippincott Williams & Wilkins. Retrieved from https://doi.org/10.1161/CIRCHEARTFAILURE.110.960716
Heart failure with preserved ejection fraction (HFPEF) is a common and increasing public health problem. Myocardial fibrosis is a key pathological feature of HFPEF. Peripheral collagen markers may reflect this excess fibrosis; however, the relation of these markers to prognosis in patients with HFPEF has not as yet been determined.
Mary MacKillop Institute for Health Research
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