Substantial skeletal muscle loss occurs during only 5 days of disuse

Journal article

Wall, Benjamin T., Dirks, Marlou L., Snijders, Tim, Senden, Joan M. G., Dolmans, John and Van Loon, Luc J. C.. (2014). Substantial skeletal muscle loss occurs during only 5 days of disuse. Acta Physiologica. 210(3), pp. 600 - 611. https://doi.org/10.1111/apha.12190
AuthorsWall, Benjamin T., Dirks, Marlou L., Snijders, Tim, Senden, Joan M. G., Dolmans, John and Van Loon, Luc J. C.
Abstract

Aim The impact of disuse on the loss of skeletal muscle mass and strength has been well documented. Given that most studies have investigated muscle atrophy after more than 2 weeks of disuse, few data are available on the impact of shorter periods of disuse. We assessed the impact of 5 and 14 days of disuse on skeletal muscle mass, strength and associated intramuscular molecular signalling responses.

Keywordsdisuse atrophy; immobilization; myostatin; skeletal muscle
Year2014
JournalActa Physiologica
Journal citation210 (3), pp. 600 - 611
PublisherWiley-Blackwell Publishing Ltd.
ISSN1748-1708
Digital Object Identifier (DOI)https://doi.org/10.1111/apha.12190
Scopus EID2-s2.0-84893737476
Page range600 - 611
Research GroupMary MacKillop Institute for Health Research
Publisher's version
File Access Level
Controlled
Place of publicationUnited Kingdom
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