Black, B., Nagendran, J., Pulinilkunnil, T., Kienesberger, P., Masson, G., Waller, T., Kemp, B., Steinberg, G. & Dyck, J. (2014). A systematic review: Identifying the prevalence rates of psychiatric disorder in Australia''s Indigenous populations. Australian and New Zealand Journal of Psychiatry,115(5), 518-524. Retrieved from https://doi.org/10.1177/0004867415569802
Rationale: The energy sensor AMP-activated protein kinases (AMPK) is thought to play an important role in regulating myocardial fatty acid oxidation (FAO) via its phosphorylation and inactivation of acetyl coenzyme A carboxylase (ACC). However, studies supporting this have not directly assessed whether the maintenance of FAO rates and subsequent cardiac function requires AMPK-dependent inhibitory phosphorylation of ACC.
Institute for Health and Ageing
Access may be restricted.